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Publications


A bio-guided investigation of Mitragyna inermis (Willd) O. Kuntze (Rubiaceae) unveils natural product isolates with potent cross-activity against sensitive and resistant Plasmodium falciparum
Malaria remains a significant global health challenge, especially in sub-Saharan Africa, with rising resistance to artemisinin-based...
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Bacterial Diversity in Deep-Sea Sediments of the North Atlantic Ocean and Their Biosynthesis of Secondary Metabolites
Oceanic bathyal benthos harbours extremotolerant microbial species living with low nutrient availability, high hydrostatic pressure, and...
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Unveiling the Mechanism of Action of Palmitic Acid, a Human Topoisomerase 1B Inhibitor from the Antarctic Sponge Artemisina plumosa
Cancer remains a leading cause of death worldwide, highlighting the urgent need for novel and more effective treatments. Natural...
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Anthoteibinenes F–Q: New Sesquiterpenes from the Irish Deep-Sea Coral Anthothela grandiflora
New technology has opened opportunities for research and exploration of deep-water ecosystems, highlighting deep-sea coral reefs as a...
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New Sesterterpenes from the Antarctic Sponge Suberites sp.
Chemical investigation of the Antarctic sponge Suberites sp. has previously led to the identification of new suberitane derivatives, some...
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Anthoteibinenes A–E from the Irish Deep-Sea Coral Anthothela grandiflora: An Amination Puzzle
Chemical investigation of extracts from the Irish deep-sea soft coral Anthothela grandiflora revealed cadinene-like sesquiterpenes,...
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Tuaimenal A, a Meroterpene from the Irish Deep-Sea Soft Coral Duva florida
(2022) Cold water benthic environments are a prolific source of structurally diverse molecules with a range of bioactivities against...
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Neosuberitenone, a New Sesterterpenoid Carbon Skeleton, from the Antarctic Sponge Suberites
(2023) Respiratory syncytial virus (RSV) is a highly contagious human pathogen that poses a significant threat to children under the age...
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Tuaimenals B–H, Merosesquiterpenes from the Irish Deep-Sea Soft Coral Duva florida with Bioactivity
(2022) Previous chemical investigation of the Irish deep-sea soft coral Duva florida led to the identification of tuaimenal A (10), a new...
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