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  • Writer's pictureezequiel cruz rosa

Bibliography of articles

Updated: Feb 2, 2023






















Kokkaliari S. et al. (2021) Marine Natural Products with Bioactivity Against Neglected Tropical Diseases. In:Kiyota H. (eds) Marine Natural Products. Topics in Heterocyclic Chemistry, vol 58. Springer, Singapore. https://doi.org/10.1007/7081_2021_56

















Kathryn M. Schoenrock, Charles D. Amsler, James B. McClintock and Bill J. Baker. Life history bias in endophyte infection of the Antarctic rhodophyte, Iridaea cordata. Bot. Mar. 2015, 58, 1-8.


Jacqueline L. von Salm, Christopher G. Witowski, Danielle H. Demers, Ryan M. Young, Laurent J. P. Calcul and Bill J. Baker. Screening fermentable chemodiversity libraries. In: “Marine Biomedicine: From Beach to Bedside,” Baker, B.J., ed., in press.



Sai L. Vankayala, Fiona Kearns, Bill J. Baker and H. Lee Woodcock. Computational ecology: Elucidating novel chemical defense mechanisms of Antarctic sea sponges. J. Chem. Info. Model., in revision.


Julie B. Schram, James B. McClintock, Charles D. Amsler and Bill J. Baker. Impacts of acute elevated seawater temperature on the feeding preferences of an Antarctic amphipod toward chemically deterrent macroalgae. Mar. Biol. 2015, 162, 425-433. DOI: 10.1007/s00227-014-2590-8


Chieu Anh Ta, Marie Freundorfer, Thien-Fah Mah, Marco Otárola-Rojas, Mario Garcia, Pablo Sanchez-Vindas, Luis Poveda, J. Alan Maschek, Bill J. Baker, Allison L. Adonizio, Kelsey Downum, Tony Durst and John T. Arnason. Inhibition of bacterial quorum sensing and biofilm formation by neotropical rainforest plants. Planta Med. 2014, 80, 343-350. DOI: 10.1055/s-0033-1360337


Jacqueline L. von Salm, Nerida G. Wilson, Brian A. Vesley, Dennis E. Kyle, Jason Cuce and Bill J. Baker. Shagenes A and B, novel tricyclic sesquiterpenes produced by an unidentified Antarctic octocoral. Org. Lett. 2014, 16, 2630-2633. DOI: 10.1021/ol500792x. PMCID: PMC4127331


Ruth E. McDowell, Charles D. Amsler, James B. McClintock and Bill J. Baker. ROS as a grazing defense in marine systems: H2O2 and wounded Ascoseira mirabilis both inhibit feeding by an amphipod grazer. J. Exp. Mar. Biol. Ecol. 2014, 458, 34-38.


Yuri Pevzner, Daniel N. Santiago, Jacqueline L. von Salm, Rainer S. Metcalf, Kenyon G. Daniel, Laurent Calcul, H. Lee Woodcock, Bill J. Baker, Wayne C. Guida and Wesley H. Brooks. Virtual target screening to rapidly identify potential protein targets of natural products in drug discovery. AIMS Mol. Sci. 2014, 1, 81-98.


Carrie Waterman, Laurent Calcul, Tina Mutka, Dennis E. Kyle, Cedric J. Pearce and Bill J. Baker. A potent antimalarial trichothecene from unidentified Hyphomycetes. Tetrahedron Lett. 2014, 55, 3989-3991.


Ruth E. McDowell, Charles D. Amsler, Dale A. Dickinson, James B. McClintock and Bill J. Baker. Reactive oxygen species and the Antarctic macroalgal wound response. J. Phycol. 2014, 50, 71-80. DOI: 10.1111/jpy.12127.


Charles D. Amsler, James B. McClintock and Bill J. Baker. Chemical mediation of mutualisms among macroalgae and mesograzers structure unique Antarctic Peninsular coastal communities. J. Phycol. 2014, 50, 1-10. DOI: 10.1111/jpy.12137.


Laurent Calcul, Carrie Waterman, Wai Sheung Ma, Matt Lebar, Charles Harter, Tina Mutka, Lindsay Morton, Patrick Maignan, Alberto Van Olphen, Dennis E. Kyle, Lilian Vrijmoed, Ka-Lai Pang, Cedric Pearce and Bill J. Baker. Screening mangrove endophytic fungi for antimalarial natural products. Mar. Drugs 2013, 11, 5036-5050. DOI:10.3390/md11125036. PCMID: PMC3877901


James B. McClintock, Charles D. Amsler and Bill J. Baker. Starfish secondary metabolites. In: Asteroidea: Biology and Ecology of Starfish, The Johns Hopkins University Press, John Lawrence, ed., 2013, 81-90. ISBN-10: 1421407876


Joseph R. Pawlik, Charles D. Amsler, Raphael Ritson-Williams, James B. McClintock, Bill J. Baker and Valerie J. Paul. Marine Chemical Ecology: A Science Born of Scuba. In: Research Discoveries: The Revolution of Science through Scuba. Smithsonian Institution Scholarly Press, Michael A. Lang, ed., 2013, 53-69.


Mario Lebrato, James B. McClintock, Margaret O. Amsler, Justin B. Ries, Hronn Egilsdottir, Charles D. Amsler, Roberta C. Challener, Julie B. Schram, Christopher L. Mah, Jason Cuce and Bill J. Baker. From the Arctic to the Antarctic: Trace and rare elemental geochemistry of echinoderm skeletons. Ecol. 2013, 94, 1434.


Margaret O. Amsler, Charles D. Amsler, Jacqueline L. von Salm, Craig F. Aumack, James B. McClintock and Bill J. Baker. Tolerance and sequestration of macroalgal chemical defenses by an Antarctic amphipod: a ‘cheater’ among mutualists. Mar. Ecol. Prog. Ser. 2013, 490, 79-90. DOI:10.3354/meps10446


Ryan M. Young, Jacqueline L. von Salm, Margaret O. Amsler, Juan Lopez-Bautista, Charles D. Amsler, James B. McClintock and Bill J. Baker. Site-specific variability in the chemical diversity of the Antarctic red alga Plocamium cartilagineum. Mar. Drugs 2013, 11, 2126-2139. DOI:10.3390/md11062126. PMCID: PMC3721224


Nerida G. Wilson, J. Alan Maschek and Bill J. Baker. An adaptive radiation driven by predation? A unique marine invertebrate species flock in Antarctica. Plos One 2013, 8 e80277. DOI: 10.1371/journal.pone.0080277. PMCID: PMC3841181


Kathryn M. Schoenrock, Charles D. Amsler, James B. McClintock and Bill J. Baker. Endophyte presence as a potential stressor on growth and survival in Antarctic macroalgal hosts. Phycologia 2013, 52, 595-599. DOI: 10:2216/13–188.1


Philip Bucolo, Charles D. Amsler, James B. McClintock and Bill J. Baker. Effects of macroalgal chemical extracts on spore behavior of the Antarctic epiphyte Elachista antarctica phaeophyacea. J. Phycol. 2012, 48, 1403-1410.


Laurent Calcul, Bo Zhang, Umesh K. Jinwal, Chad A. Dickey and Bill J. Baker. Natural products as a rich source of tau reduction agents for treatment of Alzheimer's disease. Future Med. Chem. 2012, 4, 1751-1761. PMCID: PMC3575183


J. Alan Maschek, Emily M. Mevers, Thushara Diyabalanage, Liwei Chen, Yuan Ren, Charles D. Amsler, James B. McClintock, Jie Wu and Bill J. Baker. Palmadorin chemodiversity from the Antarctic nudibranch Austrodoris kerguelenensis and inhibition of Jak2/STAT5-dependent HEL leukemia cells. Tetrahedron 2012, 68, 9095-9104.

Charles D. Amsler, James B. McClintock and Bill J. Baker. Palatability of living and dead detached Antarctic macroalgae to consumers. Antarctic Sci. 2012, 24, 589-590.

Philip Bucolo, Charles D. Amsler, James B. McClintock and Bill J. Baker. Phototactic responses of Elachista antarctica (Phaeophyceae) spores. Bot. Mar. 2012, 55, 639-642.

Jeremy Beau, Nida Mahid, Whittney Burda, Lacey Harrington, Lindsey N. Shaw, Tina Mutka, Dennis Kyle, Betty Barisic, Alberto van Olphen, and Bill J. Baker. Epigenetic tailoring for the production of anti-infective cytosporones from the mangrove endophyte Leucostoma persoonii. Mar. Drugs 2012, 10, 762-774. DOI:10.3390/md10040762. PMCID: PMC3366674


Hamel P. Sevak, James B. McClintock, J. Alan Maschek, Margaret Amsler, Craig Aumack, Kevin J. Peters, and Bill J. Baker. Algicidal activity and potential antifouling defense in macroalgae from the western Antarctic Peninsula including probable synergistic effects of multiple compounds. Bot. Mar. 2012, 55, 311-315.

James B. McClintock, Margaret O. Amsler, Robert A. Angus, Roberta C. Challener, Julie B. Schram, Charles D. Amsler, Christopher L. Mah, Jason Cuce and Bill J. Baker. Mg-Calcite composition of Antarctic echinoderms: important implications for predicting the impacts of ocean acidification. J. Geol. 2011, 119, 457-466.


Gil Koplovitz, James B. McClintock, Charles D. Amsler and Bill J. Baker. A comprehensive evaluation of the potential chemical defenses of Antarctic ascidians against sympatric fouling microorganisms. Mar. Biol. 2011, 158, 2661-2671.


Matthew D. Lebar, Kristopher N. Hahn, Tina Mutka, Patrick Maignan, Alberto van Olphen, Dennis E. Kyle, James B. McClintock, Charles D. Amsler and Bill J. Baker. CNS and antimalarial activity of synthetic meridianin and psammopemmin analogs. Bioorg. Med. Chem. 2011, 19, 5756-5762.


Charles D. Amsler, James B. McClintock and Bill J. Baker. Amphipods exclude filamentous algae from the Western Antarctic Peninsula benthos: experimental evidence. Polar Biol. 2012, 35, 171-177.


Philip Bucolo, Charles D. Amsler, James B. McClintock and Bill J. Baker. Palatability of the Antarctic rhodophyte Palmaria decipiens (Reinsch) R.W. Ricker and its endo/epiphyte Elachista antarctica Skottsberg to sympatric amphipods. J. Exp. Mar. Biol. Ecol. 2011, 396, 202-206.


Craig F. Aumack, Charles D. Amsler, James B. McClintock and Bill J. Baker. Changes in amphipod densities among macroalgal habitats in day versus night collections along the western Antarctic peninsula. Mar. Biol. 2011, 158, 1879-1885.


Jeffrey R. Jones, Matthew Lebar, Umesh K. Jinwal, Jose F. Abisambra, John Koren III, Laura Blair, John C. O’Leary, Zachary Davey, Justin Trotter, Amelia G. Johnson, Edwin Weeber, Christopher B. Eckman, Bill J. Baker and Chad A. Dickey. The diarylheptanoid (+)-aR,11S-myricanol and two flavones from Bayberry (Myrica cerifera) destabilize the microtubule associated protein tau. J. Nat. Prod. 2011, 74, 38-44. PMCID: PMC3070757


Jaime L. Noguez, Thushara Diyabalanage, Yoshinari Miyata, Xiao-Song Xie, Frederick Valeriote, Charles D. Amsler, James B. McClintock and Bill J. Baker. Palmerolide macrolides from the Antarctic tunicate Synoicum adareanum: structures and bioactivity. Bioorg. Med. Chem. 2011, 19, 6608-6614.

J. Alan Maschek, Cindy Bucher, Alberto van Olphen, Charles D. Amsler, James B. McClintock and Bill J. Baker. The pursuit of potent anti-influenza activity from the Antarctic red marine alga Gigartina skottsbergii. In: The Biological Activity of Phytochemicals, Recent Adv. Phytochem. Vol 41, D. R. Gang, ed., Springer, 2011, 41, 1-12.

Craig F. Aumack, Charles D. Amsler, James B. McClintock and Bill J. Baker. Impacts of mesograzers on epiphyte and endophyte growth associated with chemically defended macroalgae along the Western Antarctic Peninsula. J. Phycol. 2011, 47, 36-41.

Matthew D. Lebar, Lisha Luttenton, James B. McClintock, Charles D. Amsler and Bill J. Baker. Accumulation of vanadium, manganese, and nickel in Antarctic tunicates. Polar Biol. 2011, 34, 587-590.

Rob W. M. van Soest and Bill J. Baker. A new carnivorous shallow-water sponge from McMurdo Sound, Antarctica (Porifera, Poecilosclerida). Mar. Biodiversity 2011, 41, 495-501.


Jill P. Zamzow, Craig F. Aumack, Charles D. Amsler, James B. McClintock, and Bill J. Baker. Gut contents and stable isotope analyses of the Antarctic fish, Notothenia coriiceps Richardson, from two macroalgal communities. Antarctic Sci. 2011, 23, 107-116.


Matt D. Lebar and Bill J. Baker. Synthesis of the C3-14 fragment of palmerolide A using a chiral pool based strategy. Tetrahedron 2010, 66, 1557-1562.


Jill P. Zamzow, Charles D. Amsler, James B. McClintock and Bill J. Baker. Habitat choice and predator avoidance by Antarctic amphipods: the roles of algal chemistry and morphology. Mar. Ecol. Prog. Ser. 2010, 400, 155-163.


Thushara Diyabalanage, Katrin B. Iken, Charles D. Amsler, James B. McClintock and Bill J. Baker. Palmadorins A-C, sesquiterpene glycerides from the Antarctic nudibranch Austrodoris kerguelenensis. J. Nat. Prod. 2010, 73, 416-421.


Matt D. Lebar and Bill J. Baker. Synthesis and structure reassessment of psammopemmin A. Aust. J. Chem. 2010, 63, 862-866.


Hiroki Asao, Yoko Nakamura, Yukito Furuya, Shigefumi Kuwahara, Bill J. Baker and Hiromasa Kiyota. Synthesis of pteroenone and its stereoisomers, a defensive metabolite of the abducted Antarctic pteropod Clione antarctica. Helv. Chim. Acta 2010, 93, 1933-1944.


James B. McClintock, Charles D. Amsler and Bill J. Baker. Overview of the chemical ecology of benthic marine invertebrates along the Western Antarctic Peninsula. Integ. Comp. Biol. 2010, 50, 967-980.


Craig F. Aumack, Charles D. Amsler, James B. McClintock and Bill J. Baker. Chemically mediated resistance to mesoherbivory in finely branched macroalgae along the western Antarctic Peninsula. Euro. J. Phycol. 2010, 45, 19-26.

Kevin J. Peters, Charles D. Amsler, James B. McClintock and Bill J. Baker. Potential chemical defenses of Antarctic sponges against sympatric microorganisms. Polar Biol. 2010, 33, 649-658.


Margaret O. Amsler, James B. McClintock, Charles D. Amsler, Robert A. Angus and Bill J. Baker. An evaluation of sponge-associated amphipods from the Antarctic Peninsula. Antarctic Sci. 2009, 21, 579-589.


Gil Koplovitz, James B. McClintock, Charles D. Amsler and Bill J. Baker. Palatability and chemical anti-predatory defenses in common ascidians from the Antarctic peninsula. Aquatic Biol. 2009, 7, 81-92.


Wai S. Ma, Tina Mutka, Brian Vesley, Margaret O. Amsler, James B. McClintock, Charles D. Amsler, Jason A. Perman, Maya P. Singh, William M. Maiese, Michael J. Zaworotko, Dennis E. Kyle and Bill J. Baker. Norselic acids A-E, highly oxidized anti-infective steroids that deter mesograzer predation, from the Antarctic sponge Crella sp. J. Nat. Prod. 2009, 72, 1842-1846.


Charles D. Amsler, Katrin Iken, James B. McClintock and Bill J. Baker. Defenses of polar macroalgae against herbivores and biofoulers. Bot. Mar. 2009, 52, 535-546.


Charles D. Amsler, Margaret O. Amsler, James B. McClintock and Bill J. Baker. Filamentous algal endophytes in macrophytic Antarctic algae: prevalence in hosts and palatability to mesoherbivores. Phycologia 2009, 48, 324-334.


Katrin B. Iken, Charles D. Amsler, Margaret O. Amsler, James B. McClintock and Bill J. Baker. Field studies on deterrent roles of phlorotannins in Antarctic brown algae. Bot. Mar. 2009, 52, 547-558.


Kevin J. Peters, Charles D. Amsler, James B. McClintock, Rob W. M. van Soest, Bill J. Baker. Palatability and chemical defenses of sponges from the western Antarctic Peninsula. Mar. Ecol. Prog. Ser. 2009, 385, 77-85.


James B. McClintock, Margaret O. Amsler, Gil Koplovitz, Charles D. Amsler and Bill J. Baker. Observations on an association between the dexaminid amphipod Polycheria antarctica F. acanthopoda and its ascidian host Distaplia cylindrica. J. Crustacean Biol. 2009, 29, 605-608.


James B. McClintock, Robert A. Angus, Christina Ho, Charles D. Amsler and Bill J. Baker. A laboratory study of behavioral interactions of the Antarctic keystone sea star Odontaster validus with three sympatric predatory sea stars. Mar. Biol. 2008, 154, 1077-1084.


Charles D. Amsler, James B. McClintock and Bill J. Baker. Macroalgal chemical defenses in polar marine communities. In: Algal Chemical Ecology, Charles D. Amsler, ed., Springer-Verlag, Berlin, 91-103, 2008.


Christian S. Riesenfeld, Alison E. Murray and Bill J. Baker. Characterization of the microbial consortia and polyketide synthetic potential in the Palmerolide-producing tunicate, Synoicum adareanum. J. Nat. Prod. 2008, 71, 1812-1818.


James B. McClintock, Robert A. Angus, Christina P. Ho, Charles D. Amsler and Bill J. Baker. Intraspecific agonistic arm-fencing behavior in the Antarctic keystone sea star Odontaster validus influences prey acquisition. Mar. Ecol. Prog. Ser. 2008, 371, 297-300.


J. Alan Maschek and Bill J. Baker. Ecological roles of secondary metabolites from macroalgae. In: Algal Chemical Ecology, Charles D. Amsler, ed., Springer-Verlag, Berlin, 1-24, 2008.


Matthew D. Lebar, Jaime L. Heimbegner and Bill J. Baker. Cold-water marine natural products. Nat. Prod. Reports 2007, 24, 774-797.


Yusheng M. Huang, Margaret O. Amsler, James B. McClintock, Charles D. Amsler and Bill J. Baker. Patterns of gammarid amphipod abundance and species composition associated with dominant subtidal macroalgae along the western Antarctic Peninsula. Polar Biol. 2007, 30, 1417-1430.


Katrin B. Iken, Charles D. Amsler, Joanna M. Hubbard, James B. McClintock and Bill J. Baker. Allocation patterns of phlorotannins in Antarctic brown algae. Phycologia 2007, 46, 386-395.


Matthew D. Lebar and Bill J. Baker. On the stereochemistry of palmerolide A. Tetrahedron Lett. 2007, 48, 8009-8010.


Yoshinari Miyata, Thushara Diyabalanage, Charles D. Amsler, James B. McClintock, Frederick A. Valeriote and Bill J. Baker. Ecdysteroids from the Antarctic tunicate Synoicum adareanum. J. Nat. Prod. 2007, 70, 1859-1864.


James B. McClintock, Margaret O. Amsler, Charles D. Amsler and Bill J. Baker. The biochemical composition, energy content and chemical antifeedant defenses of the common Antarctic Peninsular sea stars Granaster nutrix and Neosmilaster georgianus. Polar Biol. 2006, 29, 615-623.


Thushara Diyabalanage, Charles D. Amsler, James B. McClintock and Bill J. Baker. Palmerolide A, a cytotoxic macrolide from the Antarctic tunicate Synoicum adareanum. J. Am. Chem. Soc. 2006, 128, 5630-5631.


V. Anne Fairhead, Charles D. Amsler, James B. McClintock and Bill J. Baker. Lack of defense or phlorotannin induction by UV radiation or mesograzers in Desmarestia anceps and D. menziesii. J. Phycol. 2006, 42, 1174-1183.


Eric J. Sorscher, J. Harris, Mariah Alexander, A. Rottgers, K. Hardy, Selvarangan Ponnazhagen, James F. Collawn, James B. McClintock, Charles D. Amsler, A. Webster, Joseph Maddry, Bill J. Baker, and Jeong S. Hong. Activators of viral gene expression in polarized epithelial monolayers identified by rapid-throughput drug screening. Gene Therapy 2006, 13, 781-788.


Yusheng M. Huang, James B. McClintock, Charles D. Amsler, Kevin J. Peters and Bill J. Baker. Feeding rates of common Antarctic gammarid amphipods on ecologically important sympatric macroalgae. J. Exp. Mar. Biol. Ecol. 2006, 329, 55-65.

James B. McClintock, Charles D. Amsler, Bill J. Baker and Robert W. M. van Soest. Ecology of Antarctic marine sponges: An overview. Integ. Comp. Biol. 2005, 45, 359-368.


V. Anne Fairhead, Charles D. Amsler, James B. McClintock and Bill J. Baker. Variation in phlorotannin content within two species of brown macroalgae (Desmarestia anceps and D. menziesii) from the Antarctic Peninsula. Polar Biol. 2005, 28, 680-686.


Charles D. Amsler, Ijeoma N. Okogbue, Dori M. Landry, Margaret O. Amsler, James B. McClintock and Bill J. Baker. Potential chemical defenses against diatom fouling in Antarctic macroalgae. Bot. Mar. 2005, 48, 318-322.


Kevin J. Peters, Charles D. Amsler, Margaret O. Amsler, James B. McClintock, Robert B. Dunbar and Bill J. Baker. A comparative analysis of the nutritional and elemental composition of macroalgae from the western Antarctic Peninsula. Phycologia 2005, 44, 453-463.


Charles D. Amsler, Katrin B. Iken, James B. McClintock, Margaret O. Amsler, Kevin J. Peters, Joanna M. Hubbard, F. Bruce Furrow and Bill J. Baker. A comprehensive evaluation of the palatability and chemical defenses of subtidal macroalgae from the Antarctic peninsula. Mar. Ecol. Prog. Ser. 2005, 294, 141-159.

V. Anne Fairhead, Charles D. Amsler, James B. McClintock and Bill J. Baker. Within-thallus variation in chemical and physical defenses in two species of ecologically dominant brown macroalgae from the Antarctic Peninsula. J. Exp. Mar. Biol. Ecol. 2005, 322, 1-12.


Yoko Nakamura, Hiromasa Kiyota, Bill J. Baker and Shigefumi Kuwahara. First Synthesis of (+)-pteroenone: a defensive metabolite of the abducted Antarctic pteropod Clione antarctica. Synlett 2005, 635-636.


Sridevi Ankisetty, Santhi Nandiraju, Hla Win, Young Chul Park, Charles D. Amsler, James B. McClintock, Jill A. Baker, Thushara Diyabalanage, Albert Pasaribu, Maya P. Singh, William M. Maiese, Rosa D. Walsh, Michael J. Zaworotko and Bill J. Baker. Chemical investigation of predator-deterred macroalgae from the Antarctic peninsula. J. Nat. Prod. 2004, 67, 1295-1302.


James B. McClintock, Margaret O. Amsler, Charles D. Amsler, K. J. Southworth, Chris Petrie, and Bill J. Baker. Biochemical composition, energy content and chemical anti-feedant and anti-foulant defenses of the circumpolar colonial Antarctic ascidian Distaplia cylindrica. Mar. Biol. 2004, 145, 885-894.


Sridevi Ankisetty, Charles D. Amsler, James B. McClintock and Bill J. Baker. Further membranolide diterpenes from the Antarctic sponge Dendrilla membranosa. J. Nat. Prod. 2004, 67, 1172-1174.


Katrin B. Iken and Bill J. Baker. Ainigmaptilone A: A new sesquiterpene from the Antarctic gorgonian coral Ainigmaptilon antarcticus (Octocorallia, Gorgonacea). J. Nat. Prod. 2003, 66, 888-890.


James B. McClintock, Charles D. Amsler, Margaret O. Amsler, Andy R. Mahon, Kevin Peters and Bill J. Baker. Chemical defenses in embryos and juveniles of two common Antarctic sea stars and an isopod, Antarctic Sci. 2003, 15, 339-344.

F. Bruce Furrow, James B. McClintock, Charles D. Amsler and Bill J. Baker. Surface sequestration of chemical feeding deterrents in the Antarctic sponge Latrunculia apicalis as an optimal defense against sea star spongivory. Mar. Biol. 2003, 143, 443-449.


Andy R. Mahon, Charles D. Amsler, James B. McClintock, Margaret O. Amsler and Bill J. Baker. Tissue-specific palatability and chemical defenses against macro-predators and pathogens in the common articulate brachiopod Liothyrella uva from the Antarctic Peninsula. J. Exp. Mar. Biol. Ecol. 2003, 290, 197-210.


Andy R. Mahon, Charles D. Amsler, James B. McClintock and Bill J. Baker. Chemo-tactile predator avoidance responses of the common Antarctic limpet, Nacella concinna. Polar Biol. 2002, 25, 469–473.


Charles D. Amsler, Katrin B. Iken, James B. McClintock and Bill J. Baker. Secondary metabolites from Antarctic marine organisms and their ecological implications. In: Marine Chemical Ecology, James B. McClintock and Bill J. Baker, eds., CRC Press, Boca Raton, Florida, 2001, pp. 267-300.


Charles D. Amsler, James B. McClintock and Bill J. Baker. Secondary metabolites as mediators of trophic interactions among Antarctic marine organisms. Am. Zool. 2001, 41, 17-26.


James B. McClintock, Debra Steinberg and Bill J. Baker. Invertebrate meroplankton and holoplankton. In: Marine Chemical Ecology, James B. McClintock and Bill J. Baker, eds., CRC Press, Boca Raton, Florida, 2001, pp 195-225.


Byoung Ho Moon, Young Chul Park, James B. McClintock and Bill J. Baker. Structure and bioactivity of erebusinone, a pigment from the Antarctic sponge Isodictya erinacea. Tetrahedron 2000, 56, 9057-9062.


James B. McClintock, Bill J. Baker, Charles D. Amsler and Thomas L. Barlow. Chemotactic tube-foot responses of the spongivorous sea star Perknaster fuscus to organic extracts from sponges from McMurdo Sound, Antarctic. Antarctic Sci. 2000, 12, 41-46.


Charles D. Amsler, Chris B. Moeller, James B. McClintock, Katrin B. Iken and Bill J. Baker. Chemical defense against diatoms in Antarctic marine sponges. Biofouling 2000, 16, 29-45.


Charles D. Amsler, James B. McClintock and Bill J. Baker. Chemical defenses of Antarctic marine organisms: A reevaluation of the latitudinal hypothesis. In: Antarctic ecosystems: models for wider ecological understanding. W. Davidson, C. Howard-Williams and P. Broady, eds., 2000, N.Z. Natural Sciences, Christchurch, New Zealand, pp. 158-164.


Charles D. Amsler, James B. McClintock and Bill J. Baker. An Antarctic feeding triangle: defense from predation involving a novel form of mutualism. Mar. Ecol. Prog. Ser., 1999, 183, 105-114.


Gamini S. Jayatilake and Bill J. Baker. Synthetic studies of the tridentatols. Org. Lett. 1999, 1, 661-662.


James B. McClintock, Bill J. Baker, Thomas K. Baumiller and Charles G. Messing. Lack of chemical defense in stalked crinoids supports the predation hypothesis for mesozoic bathymetric displacement. J. Exp. Mar. Biol. Ecol. 1999, 232, 1-7.


Patrick J. Bryan, James B. McClintock and Bill J. Baker. Population biology and antipredator defenses of the shallow water Antarctic nudibranch Tritoniella belli. Mar. Biol. 1998, 132, 259-265.


Byoung Ho Moon, Bill J. Baker and James B. McClintock. Purine and nucleoside metabolites from the Antarctic sponge Isodictya erinacea. J. Nat. Prod. 1998, 61, 116-118.


Charles D. Amsler, James B. McClintock and Bill J. Baker. Chemical defense against herbivory in the Antarctic marine macroalgae Iridaea cordata and Phyllophora antarctica (Rhodophyceae). J. Phycol. 1998, 34, 53-59.


James B. McClintock and Bill J. Baker. Chemical ecology in Antarctic seas. Am. Scientist 1998, 86, 254-263.


Yoichi Nakao, Wesley Yoshida, Christina M. Szabo, Bill J. Baker and Paul J. Scheuer. More peptides and other diverse constituents of the marine mollusk Philinopsis speciosa. J. Org. Chem. 1998, 63, 3272-3280.


Gamini S. Jayatilake, Bill J. Baker and James B. McClintock. Rhapsamine, a novel cytotoxic agent from the Antarctic sponge Leucetta leptorhapsis. Tetrahedron Lett. 1997, 38, 7507-7510.


Richard D. Adams, John H. Yamamoto, Agnes Holmes and Bill J. Baker. Catalytic transformations of thiiranes by (thiirane)W(CO)5 complexes. Organomet. 1997, 15, 1430-1439.


James B. McClintock and Bill J. Baker. Palatability and chemical defense of eggs, embryos and larvae of shallow-water Antarctic marine invertebrates. Mar. Ecol. Prog. Ser. 1997, 154, 121-131.


James B. McClintock and Bill J. Baker. A review of the chemical ecology of Antarctic marine invertebrates. Am. Zool., 1997 37, 329-342.


Simona De Marino, Maria Iorizzi, Franco Zollo, Luigi Minale, Charles D. Amsler, Bill J. Baker and James B. McClintock. Isolation, structure elucidation and biological activity of the steroid oligoglycosides and polyhydroxysteroids from the Antarctic sea star Acodontaster conspicuus. J. Nat. Prod. 1997, 60, 959-966.


Gamini S. Jayatilake and Bill J. Baker. Comparison of terpenoid cytotoxin concentrations in laboratory-maintained versus wild-collected Spongia sp. J. Nat. Toxins 1996, 5, 287-293.


Bill J. Baker. β-Carboline and isoquinoline alkaloids from marine organisms. In: Alkaloids: Chemical and Biological Perspectives, Volume 10, S.W. Pelletier, ed., 1996, Pergamon Press, Oxford, pp. 357-407.


Gamini S. Jayatilake, Maureen P. Thornton, Alan C. Leonard, Julia E. Grimwade and Bill J. Baker. Metabolites from an Antarctic sponge-associated bacterium, Pseudomonas aeruginosa. J. Nat. Prod. 1996, 59, 293-296.


Aimin Yang, Bill J. Baker, Julia E. Grimwade, Alan C. Leonard and James B. McClintock. Discorhabdin alkaloids from the Antarctic sponge Latrunculia apicalis. J. Nat. Prod. 1995, 58, 1596-1599.


Gamini S. Jayatilake, Bill J. Baker and James B. McClintock. 1,3,5’-Triacetoxystilbene, a plant growth regulator, from the Antarctic sponge Kirkpatrickia variolosa. J. Nat. Prod. 1995, 58, 1958-1960.


Hyin He, Palaniappan Kulanthaivel, Bill J. Baker, Kiyomi Kalter, Jim Darges, Divann Cofield, Leslie Wolff and Laurel Adams. New anti-inflammatory 9,11-secosterols from the gorgonian Pseudopterogorgia sp. Tetrahedron 1995, 51, 51-58.


Bill J. Baker, Bob Kopitzke, Wesley Yoshida and James B. McClintock. Chemical and ecological studies of the Antarctic sponge Dendrilla membranosa. J. Nat. Prod. 1995, 58, 1459-1462.


Patrick Bryan, Wesley Yoshida, James B. McClintock and Bill J. Baker. Ecological role for pteroenone, a novel antifeedant from the conspicuous Antarctic pteropod Clione antarctica. Mar. Biol. 1995, 122, 271-277.


Wesley Yoshida, Patrick Bryan, Bill J. Baker and James B. McClintock. Pteroenone, the feeding deterrent substance from the Antarctic pteropod Clione antarctica. J. Org. Chem. 1995, 60, 780-782.


James B. McClintock, Bill J. Baker, Mark Slattery, John N. Heine, Patrick J. Bryan, Wesley Yoshida, Michael T. Davies-Coleman and D. John Faulkner. Chemical defense of the common Antarctic nudibranch Tritonella belli Eliot (Mollusca: Tritonidae) and its prey, Clavularia frankliniana Rouel (Cnidaria: Octocorallia). J. Chem. Ecol. 1994, 20, 3361-3372.


James B. McClintock, Bill J. Baker, Mark T. Hamann, Wesley Yoshida, Mark Slattery, John N. Heine, Patrick J. Bryan, Gamini S. Jayatilake and Byoung Ho Moon. Homarine as a feeding deterrent in common shallow-water Antarctic lamellarian gastropod Marsineopsis mollis: a rare example of chemical defense in a marine prosobranch. J. Chem. Ecol. 1994, 20, 2539-2549.


Bill J. Baker and Paul J. Scheuer. The punaglandins: 10-Chloroprostanoids from the octocoral Telesto riisei. J. Nat. Prod. 1994, 57, 1346-1353.


Hyin He, Palaniappan Kulanthaivel and Bill J. Baker. New cytotoxic sesterterpenes from the marine sponge Spongia sp. Tetrahedron Lett. 1994, 35, 7189-7192.


Guo Q. Shen and Bill J. Baker. Biosynthetic studies of eudistomin H in the tunicate Eudistoma olivaceum. Tetrahedron Lett. 1994, 35, 4923-4926.


Guo Q. Shen and Bill J. Baker. Biosynthetic studies of the eudistomins in Eudistoma olivaceum. Tetrahedron Lett. 1994, 35, 1141-1144.


James B. McClintock, Bill J. Baker, Mark Slattery, Mark Hamann, Robert Koptizke and John Heine. Chemotactic tube-foot responses of the spongivorous sea star Perknaster fuscus to organic extracts from Antarctic sponges. J. Chem. Ecol. 1994, 20, 859-870.


Bill J. Baker and Russell G. Kerr. Biosynthesis of marine sterols. In: Topics in Current Chemistry. Vol. 167, Paul J. Scheuer, ed., 1993, Springer-Verlag, Berlin, pp 1-31.


Russell G. Kerr and Bill J. Baker. Marine sterols. Nat. Prod. Rep. 1991, 8, 465-497.


Ronald J. Parry, Shyhchen Ju and Bill J. Baker. The synthesis of 5(R)-5[3H]-l-ornithine and 5(S)-5[3H]-l-ornithine. J. Lab. Comp. Radiopharm. 1991, 8, 633-643.


Russell G. Kerr, Bill J. Baker, Sutinah L. Kerr and Carl Djerassi. Biosynthesis of marine lipids 27. Demonstration of sterol side chain dealkylation using cell-free extracts of marine sponges. Tetrahedron Lett. 1990, 31, 5425-5428.


Ronald J. Parry, Izura Y. Arzu, Shyhchen Ju and Bill J. Baker. Biosynthesis of sinefungin. J. Am. Chem. Soc. 1989, 111, 8981-8982.


Bill Baker, Lal Ratnapala, M. P. D. Mahindaratne, E. Dilip de Silva, L. M. V. Tillekeratne, Jeong H. Jeong, Paul J. Scheuer and Karl Seff. Lankalapuol A and B: Two cis-eudesmanes from the sea hare Aplysia dactylomela. Tetrahedron 1988, 44, 4695-4701.


Masaaki Suzuki, Yasushi Morita, Akira Yanagisawa, Bill J. Baker, Paul J. Scheuer and Ryoji Noyori. Synthesis and structural revision of (7E)- and (7Z)-punaglandin 4. J. Org. Chem. 1988, 53, 286-295.


Bill J. Baker, Paul J. Scheuer and James N. Shoolery. Papuamine, an antifungal pentacyclic alkaloid from a marine sponge, Haliclona sp. J. Am. Chem. Soc. 1988, 110, 965-966.


Masaaki Suzuki, Yasushi Morita, Akira Yanagisawa, Ryoji Noyori, Bill J. Baker and Paul J. Scheuer. Punaglandins, structural revision by chemical synthesis. J. Am. Chem. Soc., 1986, 108, 5021-5022.


Bill J. Baker, Roy K. Okuda, Patrick T. K. Yu and Paul J. Scheuer. Punaglandins: Halogenated eicosanoids from the octocoral Telesto riisei. J. Am. Chem. Soc. 1985, 107, 2976-2977.


Edited Books:

Marine Biomedicine: From Beach to Bedside. Bill J. Baker, Ed. CRC Press, Boca Raton, Florida, in press.

Marine Chemical Ecology. James B. McClintock and Bill J. Baker, Eds. CRC Press, Boca Raton, Florida, 2001, 624 pages (ISBN: 0849390648).


Patents, Patent applications and Disclosures (3 awarded US patents to date):




Nhan Kim Pham, Laurent J. Calcul, Bill J. Baker. Discovery of new alkaloids from the Antarctic tunicate Synoicum sp.

Christopher Witowski, John Alan Maschek, Brian Vesely, Dennis E. Kyle and Bill J. Baker. Semisynthetic antileishmanial compounds based on membranolide diterpene scaffold. Disclosure 14B109PR, filed 1 Aug 2014; Provisional Patent 62/032,243, filed 1 Aug 2014

Umesh Jinwal, Bill J. Baker and Laurent Calcul. Compounds and Related Methods for the Treatment of Neurodegenerative Diseases. Disclosure 13A073, filed 6 May 2013; Provisional Patent 13A073PR, Serial Number 13A073, filed 6 May 2013.

Laurent J.-P. Calcul, Carrie A. Waterman, Bill J. Baker, Cedric J. Pearce, Dennis E. Kyle and Tina Mutka. A potent antimalarial trichothecene from unidentified hyphomycetes. Disclosure 12A038 filed 27 Mar 2012, Provisional Patent Application 12A038PR filed 21 Jun 2012.

Chad Dickey, Umesh Jinwal, Bill J. Baker and Laurent Calcul. Synthetic derivatives of myricanol. Disclosure 11B190, filed 8 Dec 2011; Provisional Patent Application 11B190PR, filed 6 Apr 2012.

Patent Application 11B190PRWO, filed 8 Apr 2013.

Jeremy Beau, Lindsey Shaw, Dennis Kyle, Alberto van Olphen and Bill J. Baker. Anti-infective cytosporones from the mangrove endophyte Leucostoma persoonii. Disclosure, 11B155 filed 5 Oct 2011.

Chad Dickey, Jeffrey Jones, Matthew Lebar and Bill J. Baker. Materials and methods for reduction of protein Tau and treatment of neurodegenerative diseases. Disclosure 10A056, filed 10 May 2010; Provisional Patent Application 10A056PR, filed 23 Jul 2010.

Patent Application 10A056PRWO, Serial Number 11/045213, filed 25 Jul 2011.

Patent Application 10A056PRWOUS, Serial Number 13/810,362, filed 15 Jan 2013.

Alberto van Olphen, Dennis Kyle, Cynthia Bucher, Alan Maschek and Bill J. Baker. Novel antiviral compounds from marine extracts. Disclosure 08A045, filed 19 May 2008; Provisional Patent Application 08A045PR, Serial Number 61/110,310, filed 31 Oct 2008.

Patent Application 08A045PRC, Serial Number 12/610,657, filed 2 Nov 2009.

Patent Application 08045PRCC, Serial Number 13/007,380, filed 14 Jan 2011. Patent 8,940,945 awarded 27 Jan 2015.

Thushara Diyabalanage, James B. McClintock, Charles D. Amsler and Bill J. Baker. Cytotoxin compounds and method of isolation. Disclosure 04A002, filed 20 Jan 2004; Provisional Patent Application 04A002PR, Serial Number 60/717,598, filed 16 Sept 2004.

Patent Application 04A002PRCWOCA , Serial Number 10/906,386, filed 17 Jan 2005, Patent 7,625,885, awarded 1 Dec 2009; International Patent Application 04A002PR2WO, PCT/US2006/036484 (Canada), 200680036645.4 (China), filed 18 Sept 2006.

Patent Application 04A002PR2WO, Serial Number 12/066,938, filed 28 Aug 2008; Patent 8,669,376, awarded 11 Mar 2014.

Patent Application 04A002PR2WO, Serial Number 12/618,461, filed 13 Nov 2009.


Publications, not Peer Reviewed (18 total):

Bill J. Baker. Carl Djerassi, 1928-2015. ASP Newsletter, Spring 2015.

Bill J. Baker. Field Notes: Field Camps in Antarctica. ASP Newsletter, Summer 2014.

James B. McClintock, Charles D. Amsler, Amy L. Moran, H. Arthur Woods and Bill J. Baker. Introduction to the symposium: Advances in Antarctic marine biology. Integ. Comp. Biol. 2010, 50, 948-949.

Bill J. Baker. The deepwater horizon oil spill: Impacts on natural products resources. ASP Newsletter, Winter 2010.

Bill J. Baker, Roy K. Okuda and Guy Carter. American Society of Pharmacognosy History, 2006-2009. In: ASP History, Gordon Cragg, ed., 2009.

Charles D. Amsler, Katrin Iken, James B. McClintock and Bill J. Baker. Defenses of polar macroalgae against herbivores and biofoulers. In: Biology of Polar Benthic Algae, Walter de Gruyter GmbH and Co. KH, Göttingen, Christian Wiencke, ed.,2011, pp. 101-119. [NOTE: This is a slightly updated version of our paper: Bot. Mar. 2009, 52, 535-546.]

Katrin Iken, Charles D. Amsler, Margaret O. Amsler, James B. McClintock and Bill J. Baker. Field studies on deterrent roles of phlorotannins in Antarctic brown algae. In: Biology of Polar Benthic Algae, Walter de Gruyter GmbH and Co. KH, Göttingen, Christian Wiencke, ed., 2011, pp. 121-138. [NOTE: This is a slightly updated version of our paper: Bot. Mar. 2009, 52, 547-558.]

Bill J. Baker. In from the cold. Chem. Sci. 2007, 4, C47.

Bill J. Baker. Diving at the end of the earth. Slate, 2007, 21-22.

Michael C. L. Vickery, Charles D. Amsler, James B. McClintock and Bill J. Baker. Secondary metabolite biosynthesis at ambient temperature in Antarctic sponge–derived bacterium, Pseudomonas aeruginosa. Antarctic J. U.S. 2005, 33, 47–50.

James B. McClintock, Charles D. Amsler, and Bill J. Baker. Introduction to the symposium: Antarctic marine biology. Am. Zool., 2001, 41, 1-2.

Charles D. Amsler, James B. McClintock, Dominic Tedeschi, Kenneth H. Dunton, and Bill J. Baker. Quantitative estimation of the phlorotannin content of three Antarctic brown macroalgae. Antarctic J. U.S., 1997, 32, 84-85.

Bill J. Baker, Thomas L. Barlow, and James B. McClintock. Evaluation of the functional role of suberitenones A and B from the sponge Suberites sp. found in McMurdo Sound, Antarctica. Antarctic J. U.S., 1997, 32, 90-91.

James B. McClintock and Bill J. Baker. Chemical feeding deterrent properties of the benthic algae Phyllophora antarctica and Iridaea cordata from McMurdo Sound, Antarctica. Antarctic J. U.S., 1995, 30, 155-157.

Bill J. Baker, Wesley Yoshida and James B. McClintock. Chemical constituents of four sponges from McMurdo Sound, Antarctica. Antarctic J. U.S., 1994, 29, 153-155.

James B. McClintock, Patrick J. Bryan, Mark Slattery, Bill J. Baker, Wesley Yoshida, Mark Hamann and John N. Heine. Chemical ecology of three Antarctic gastropods. Antarctic J. U.S., 1994, 29, 151-153.

James B. McClintock, Mark Slattery, Bill J. Baker and John N. Heine. Chemical ecology of Antarctic sponges from McMurdo Sound, Antarctica: Ecological aspects. Antarctic J. U. S., 1993, 28, 134-135.

Bill J. Baker, Bob Kopitzke, Mark Hamann and James B. McClintock. Chemical ecology of Antarctic sponges from McMurdo Sound, Antarctica: Chemical aspects. Antarctic J. U. S., 1993, 28, 132-133.

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